⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL7468202 | 0.97 | PARP1 (0.89) | — | |
| Benzamide SCHEMBL7108646 | 0.97 | PARP1 (0.89) | — | |
| Benzamide SCHEMBL3870712 | 0.97 | PARP1 (0.89) | — | |
| Benzamide SCHEMBL29618402 | 0.97 | — | — | |
| Benzamide SCHEMBL1222101 | 0.97 | PARP1 (1.00) | — | |
| Benzamide SCHEMBL6690447 | 0.97 | PARP1 (1.00) | — | |
| Benzamide SCHEMBL16352 | 0.97 | — | — | |
| Benzamide SCHEMBL30112947 | 0.97 | PARP1 (1.00) | — | |
| SCHEMBL21755166 | 0.97 | PARP1 (1.00) | — | |
| Benzamide SCHEMBL1332331 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511521-B | Polyallylbenzamide-graphene hydrogel and preparation method thereof | 吉林省七维生物科技有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-110511521-B | Polyallylbenzamide-graphene hydrogel and preparation method thereof | 吉林省七维生物科技有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-111992189-A | Adsorption film for biomembrane DGT device, preparation method and application | 南京维申环保科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-109053697-A | A kind of pyrimidines and preparation method thereof for anticancer | 张淑华 | 2018-12-21 | — | — | CN | disclosed |
| CN-105188704-B | Substituted Pyrrolopyrimidine compounds, its composition and use its treatment method | 西格诺药品有限公司 | 2017-09-19 | — | — | CN | disclosed |
| US-20090099210-A1 | ENANTIOMERS OF SELECTED FUSED HETEROCYCLICS AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | disclosed |
| US-7498333-B2 | Enantiomers of selected fused heterocyclics and uses thereof | ASTRAZENECA AB (SE) | 2009-03-03 | — | — | US | disclosed |
| US-20080293744-A1 | Enantiomers of Selected Fused Pyrimidones and Uses in the Treatment and Prevention of Cancer | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
| US-20080153854-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | US | disclosed |
| US-20070249636-A1 | Selected Fused Heterocyclics and Uses Thereof | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | US | disclosed |
| US-20060281714-A1 | Combinations of a cathepsin k inhibitor and a bisphosphonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss | ZIMMERMANN JOHANN | 2006-12-14 | — | — | US | disclosed |
| US-20060063751-A1 | Novel fused heterocycles and uses thereof | ASTRAZENECA AB (SE) | 2006-03-23 | — | — | US | disclosed |
| US-20060041128-A1 | Selected fused heterocyclics and uses thereof | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | US | disclosed |
| US-20060041129-A1 | Enantiomers of selected fused heterocyclics and uses thereof | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | US | disclosed |