Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968497 | 0.88 | ADORA3 (0.62) | DHFRKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL41999 | 0.83 | ADORA3 (0.49) | DHFRKDM4EHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1895412 | 0.82 | ADORA3 (0.48) | DHFRKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL29108569 | 0.79 | ADORA3 (0.43) | DHFRKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL42351 | 0.78 | NOS1 (0.55) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL18042289 | 0.76 | KDM4E (0.52) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL27886638 | 0.76 | ALDH1A1 (0.47) | DHFRKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL26968382 | 0.75 | ADORA3 (0.71) | GAAADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL26968493 | 0.74 | ADORA3 (0.70) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL26968368 | 0.73 | ADORA3 (0.48) | KDM4EHPGDALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036730-A | Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof | 中山大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122036730-A | Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof | 中山大学 | 2026-05-15 | — | — | CN | disclosed |