SCHEMBL38656126

SCHEMBL38656126

COc1ccc(C(C)(C)C(=O)O)cn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 2/20 0.49
SLC22A12 Q96S37 1/20 0.46
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
NPC1 O15118 5/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 2/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
POLB P06746 1/20 0.41
LMNA P02545 4/20 0.41
HTT P42858 1/20 0.41
PABPC1 P11940 2/20 0.40
OXTR P30559 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
SIRT6 Q8N6T7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31292187 0.85 BRS3 (0.50) NNMTSLC22A12MKNK1MKNK2KMT2A
SCHEMBL38655088 0.83 MAPT (0.57) MAPTPOLBLMNA
SCHEMBL22285418 0.81 NNMT (0.47) NNMTSLC22A12MKNK1MKNK2KMT2A
SCHEMBL38654796 0.81 ACACB (0.44) KDM4EMAPTNPC1RAB9AAKR1C3
SCHEMBL3767025 0.79 MAP4K4 (0.43) SLC22A12KMT2AMAPTAKR1C3AKR1C2
SCHEMBL11713827 0.79 AKR1C3 (0.45) NNMTSLC22A12AKR1C3AKR1C2LMNA
SCHEMBL31292542 0.79 MRGPRX4 (0.39) MAPTLMNA
SCHEMBL7961130 0.78 P4HA1 (0.45) KMT2AMAPTAKR1C3AKR1C2
SCHEMBL28756372 0.78 NNMT (0.47) NNMTSLC22A12MKNK1MKNK2KMT2A
SCHEMBL22079377 0.77 NNMT (0.48) NNMTMKNK1MKNK2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099466-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2026-05-15 WO disclosed