SCHEMBL38656191

SCHEMBL38656191

CC(C)(C)OC(=O)c1ccc(-c2ccc([C@H]3CCCN3C(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.50
NPC1 O15118 1/20 0.48
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
USP30 Q70CQ3 2/20 0.44
UCHL1 P09936 1/20 0.43
PTPN2 P17706 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
GPR119 Q8TDV5 4/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38655765 1.00 RIPK1 (0.50) RIPK1NPC1CA12CA1CA2
SCHEMBL38658889 0.90 RIPK1 (0.53) RIPK1NPC1CA12CA1CA2
SCHEMBL1653727 0.89 NPC1 (0.52) RIPK1NPC1USP30UCHL1ALDH1A1
SCHEMBL1655270 0.86 RIPK1 (0.53) RIPK1NPC1UCHL1ALDH1A1LMNA
SCHEMBL18406188 0.86 NPC1 (0.63) RIPK1NPC1UCHL1GPR119ALDH1A1
SCHEMBL5458875 0.85 NPC1 (0.48) RIPK1NPC1USP30UCHL1ALDH1A1
SCHEMBL30678216 0.85 GPR119 (0.53) RIPK1NPC1UCHL1GPR119ALDH1A1
SCHEMBL2130466 0.83 NPC1 (0.48) RIPK1NPC1UCHL1GPR119ALDH1A1
SCHEMBL23064586 0.83 RIPK1 (0.52) RIPK1NPC1UCHL1GPR119ALDH1A1
SCHEMBL22688967 0.83 NPSR1 (0.54) RIPK1NPC1UCHL1GPR119ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR RIPK1 4760/4885NPC1 211/4885CA12 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.