SCHEMBL38656231

SCHEMBL38656231

C[Si](C)(C)CCOCn1nnc2ccc(Br)cc2c1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 5/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
RAB9A P51151 3/20 0.40
MAPT P10636 2/20 0.40
DGAT1 O75907 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 2/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38656278 0.90 KMT2A (0.41) MEN1HTTKMT2ANPC1SMN1; SMN2
SCHEMBL26645068 0.82 DGAT1 (0.42) MEN1KMT2ANPC1RAB9ADGAT1
SCHEMBL3782203 0.80 DGAT1 (0.42) MEN1KMT2ANPC1RAB9ADGAT1
SCHEMBL8351468 0.79 MEN1 (0.51) MEN1HTTKMT2ANPC1RAB9A
SCHEMBL38656212 0.78 NPC1 (0.43) MEN1KMT2ANPC1SMN1; SMN2RAB9A
SCHEMBL38657054 0.78 MCL1 (0.54) RAB9ADGAT1POLBLMNAMCL1
SCHEMBL29991937 0.77 ATM (0.47) MEN1HTTKMT2ANPC1SMN1; SMN2
SCHEMBL20401447 0.76 NPC1 (0.43) MEN1KMT2ANPC1SMN1; SMN2RAB9A
SCHEMBL12963695 0.75 ALDH1A1 (0.64) MEN1HTTKMT2ANPC1SMN1; SMN2
SCHEMBL23042322 0.74 DGAT1 (0.42) MEN1HTTKMT2ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR MEN1 1814/4885HTT 1205/4885KMT2A 4321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.