Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657821 | 0.95 | GRM5 (0.33) | GRM5TSHRCYP3A4CYP2C19USP2 | |
| SCHEMBL38659539 | 0.88 | HSD11B1 (0.34) | GRM5TSHRCYP3A4CYP2C19USP2 | |
| SCHEMBL31558702 | 0.88 | SPR (0.33) | CYP3A4CYP2C19USP2CYP1A2HIF1A | |
| SCHEMBL17850612 | 0.87 | — | — | |
| SCHEMBL2386472 | 0.85 | CYP2D6 (0.49) | TSHRCYP3A4CYP2C19USP2ALDH1A1 | |
| SCHEMBL38657618 | 0.82 | FFAR2 (0.30) | — | |
| SCHEMBL30968095 | 0.82 | CYP2D6 (0.33) | TSHRCYP3A4CYP2C19USP2ALDH1A1 | |
| SCHEMBL21581449 | 0.81 | USP2 (0.45) | TSHRCYP3A4CYP2C19USP2ALDH1A1 | |
| SCHEMBL38658469 | 0.78 | TSHR (0.42) | TSHRCYP3A4CYP2C19USP2ALDH1A1 | |
| SCHEMBL3342266 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |