Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87054 | 0.76 | ADORA2A (0.49) | ADORA2ASMN1; SMN2ADORA3 | |
| Bromide SCHEMBL80836 | 0.74 | ADORA2A (0.48) | ADORA2ASMN1; SMN2ADORA3 | |
| SCHEMBL21063123 | 0.72 | ADORA2A (0.47) | ADORA2AADORA1PDE10A | |
| SCHEMBL29995283 | 0.72 | ADORA2A (0.47) | ADORA2AADORA1PDE10A | |
| SCHEMBL21063018 | 0.71 | KDM4E (0.45) | ADORA2ASMN1; SMN2ADORA1ADORA3 | |
| SCHEMBL38657824 | 0.71 | GRM2 (0.48) | ADORA2ACDK2ADORA1 | |
| SCHEMBL21063161 | 0.69 | ADORA2A (0.44) | ADORA2ASMN1; SMN2ADORA1PDE10AADORA3 | |
| SCHEMBL29996830 | 0.69 | ADORA2A (0.44) | ADORA2ASMN1; SMN2ADORA1PDE10AADORA3 | |
| SCHEMBL23948351 | 0.68 | PDE2A (0.47) | SMN1; SMN2PDE10APARP1 | |
| SCHEMBL1010207 | 0.66 | DHFR (0.45) | ADORA2ASMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |