Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349236 | 0.93 | ATM (0.65) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL11596560 | 0.91 | ATM (0.64) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL10624502 | 0.89 | ATM (0.67) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL28506897 | 0.89 | ATM (0.67) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL135162 | 0.89 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL9324919 | 0.89 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| Benzene SCHEMBL9243917 | 0.89 | ALDH1A1 (0.57) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL134300 | 0.86 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL134024 | 0.86 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL27510 | 0.86 | ALDH1A1 (0.59) | ATMTDP1L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014055-A1 | PREPARATION OF 2,5-DICHLOROBENZOPHENONES | MAXDEM INCORPORATED (US) | 1993-07-22 | — | — | WO | claimed |
| US-5210313-A | Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids | MAXDEM INCORPORATED (US) | 1993-05-11 | — | — | US | claimed |
| WO-2013055467-A2 | METHODS AND COMPOSITIONS FOR BONDING SILICONE POLYMERS TO HAIR AND NAILS | LIQWD, INC. (US) | 2013-04-18 | — | — | WO | disclosed |
| CN-1353609-B | Amide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO | 2011-07-13 | — | — | CN | disclosed |
| US-20090023722-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-22 | — | — | US | disclosed |
| WO-2008131119-A2 | COMPOSITION AND METHOD FOR CANCER TREATMENT AND PREVENTION | ACROPOLIS PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080261898-A1 | COMPOSITION AND METHOD FOR CANCER TREATMENT AND PREVENTION | ACROPOLIS PHARMACEUTICALS, INC. | 2008-10-23 | — | — | US | disclosed |
| US-20080261898-A1 | COMPOSITION AND METHOD FOR CANCER TREATMENT AND PREVENTION | ACROPOLIS PHARMACEUTICALS, INC. | 2008-10-23 | — | — | US | disclosed |
| US-7393859-B2 | Amide substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1379525-B1 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMA INC (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1210344-A1 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2002-06-05 | — | — | EP | disclosed |
| EP-1208104-A2 | TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES | AGOURON PHARMACEUTICALS, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1187613-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001016136-A2 | TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES | AGOURON PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001012627-A1 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000076505-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-1993014055-A1 | PREPARATION OF 2,5-DICHLOROBENZOPHENONES | MAXDEM INCORPORATED (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5210313-A | Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids | MAXDEM INCORPORATED (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023722-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | IFNG, IRF3, EIF2AK2 | ATM 1312/4885TDP1 3705/4885L3MBTL1 2741/4885 |
| US-20080261898-A1 | COMPOSITION AND METHOD FOR CANCER TREATMENT AND PREVENTION | VEGFA, MKI67, HDGF | ATM 1033/4885TDP1 2844/4885L3MBTL1 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.