Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.61 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | MAOA | P21397 | 6/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866195 | 1.00 | CALML3 (0.61) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL1222791 | 0.85 | CALML3 (0.67) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL1222787 | 0.85 | CALML3 (0.67) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL10033715 | 0.85 | CALML3 (0.67) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL1556157 | 0.84 | CALML3 (0.55) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL5809554 | 0.84 | MAOA (0.67) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1556212 | 0.84 | CALML3 (0.45) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1557789 | 0.84 | CALML3 (0.45) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1556154 | 0.84 | CALML3 (0.55) | CALML3MAOBMAOACYP2C19CYP3A4 | |
| SCHEMBL1556211 | 0.84 | MAOA (0.67) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210121449-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2021-04-29 | — | — | US | disclosed |
| US-20200078345-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2020-03-12 | — | — | US | disclosed |
| US-20180344716-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2018-12-06 | — | — | US | disclosed |
| US-20170333414-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2017-11-23 | — | — | US | disclosed |
| US-20170049763-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2017-02-23 | — | — | US | disclosed |
| US-9163043-B2 | Oxazolidinone derivatives | DONG-A ST CO., LTD. (KR) | 2015-10-20 | — | — | US | disclosed |
| US-20140350059-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A ST CO LTD (KR) | 2014-11-27 | — | — | US | disclosed |
| US-20130281492-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | TRIUS THERAPEUTICS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8420676-B2 | Oxazolidinone derivatives | DONG-A PHARMACEUTICALS CO. LTD. (KR) | 2013-04-16 | — | — | US | disclosed |
| US-20090192197-A1 | Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes Torezolid phosphate | DONG-A PHARM. CO., LTD. (KR) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049763-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20130281492-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20210121449-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20200078345-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20090192197-A1 | Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes Torezolid phosphate | ALPI, TPI1, SI | CALML3 2192/4885MAOB 3591/4885MAOA 3819/4885 |
| US-20170333414-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20140350059-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
| US-20180344716-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | ALPI, OXA1L, SI | CALML3 3337/4885MAOB 1905/4885MAOA 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.