Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | BRD4 | O60885 | 6/20 | 0.69 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 2/20 | 0.59 |
| ▸ | TOP2A | P11388 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514799 | 0.82 | BRD4 (1.00) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL23124 | 0.82 | BRD4 (1.00) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL3297016 | 0.82 | BRD4 (0.60) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL8381776 | 0.81 | BRD4 (0.97) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL22118772 | 0.81 | BRD4 (0.68) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL28669706 | 0.80 | NPC1 (0.63) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL1060507 | 0.79 | MKNK1 (0.72) | NPC1RAB9ABRAFTOP2ALMNA | |
| SCHEMBL6463477 | 0.78 | BRD4 (0.92) | BRD4NT5C2NT5EBRAFTOP2A | |
| SCHEMBL38666421 | 0.78 | BRD4 (0.66) | NPC1RAB9ABRD4NT5C2NT5E | |
| SCHEMBL29501954 | 0.78 | LMNA (0.60) | NPC1RAB9ABRD4NT5C2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749980-B2 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. | 2007-05-31 | — | — | US | disclosed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5656264-A | ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE | SANSYO SEIYAKU CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | P2RX3, P2RX5, P2RX1 | NPC1 950/4885RAB9A 3122/4885BRD4 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.