SCHEMBL386670

SCHEMBL386670

CCCCC=COCCC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 4/20 0.38
LPAR2 Q9HBW0 3/20 0.38
LPAR1 Q92633 2/20 0.38
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
FAAH O00519 2/20 0.34
TRPV1 Q8NER1 1/20 0.34
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142279 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL1142501 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL1142241 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL4433841 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL5435626 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL1142346 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL4433840 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL5435629 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL12156855 0.91 FAAH (0.46) LPAR3LPAR2LPAR1TSHRFAAH
SCHEMBL16863887 0.90 LPAR3 (0.38) LPAR3LPAR2LPAR1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111621279-A Imbibition oil displacement agent for improving recovery ratio in middle and later periods of oilfield development 赛科思能源技术(重庆)有限责任公司 2020-09-04 CN claimed
CN-111621279-A Imbibition oil displacement agent for improving recovery ratio in middle and later periods of oilfield development 赛科思能源技术(重庆)有限责任公司 2020-09-04 CN disclosed
US-8101650-B2 Method for treating a immunology-related disease DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-01-24 US disclosed
US-8067396-B2 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2011-11-29 US disclosed
US-20100035842-A1 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2010-02-11 US disclosed
US-20090326038-A1 Method for treating a immunology-related disease SANKYO COMPANY, LIMITED (JP) 2009-12-31 US disclosed
US-7638551-B2 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2009-12-29 US disclosed
EP-1471054-B1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE DAIICHI SANKYO CO LTD (JP) 2009-07-01 EP disclosed
CN-101025568-A Photosensitive resin composition SANYO CHEMICAL IND LTD (JP) 2007-08-29 CN disclosed
US-20070142335-A1 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2007-06-21 US disclosed
US-20070105933-A1 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-05-10 US disclosed
EP-1300405-B1 AMINO ALCOHOL DERIVATIVES SANKYO CO (JP) 2007-04-18 EP disclosed
US-7199150-B2 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-04-03 US disclosed
US-6964976-B2 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2005-11-15 US disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
US-20040132784-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-08 US disclosed
US-6723745-B2 PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL SANKYO COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030236297-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2003-12-25 US disclosed
EP-1300405-A1 AMINO ALCOHOL DERIVATIVES Sankyo Company, Limited (JP) 2003-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236297-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LPAR3 2545/4885LPAR2 2630/4885LPAR1 1722/4885
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these PHOSPHO1, CD4, FCGRT LPAR3 784/4885LPAR2 756/4885LPAR1 354/4885
US-20040132784-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LPAR3 2545/4885LPAR2 2630/4885LPAR1 1722/4885
US-20090326038-A1 Method for treating a immunology-related disease C3AR1, HRH3, HRH2 LPAR3 143/4885LPAR2 169/4885LPAR1 133/4885
US-20070105933-A1 Amino alcohol compounds ADH1C, C9, SSB LPAR3 334/4885LPAR2 446/4885LPAR1 321/4885
US-20070142335-A1 Amino alcohol compounds or phosphonic acid derivatives thereof HRH3, C3AR1, HRH4 LPAR3 64/4885LPAR2 76/4885LPAR1 33/4885
US-20100035842-A1 Amino alcohol compounds or phosphonic acid derivatives thereof PHOSPHO1, ADH1C, ADH1A LPAR3 102/4885LPAR2 126/4885LPAR1 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.