⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL154308 | 0.75 | — | — | |
| Iodide SCHEMBL1686563 | 0.75 | — | — | |
| Bromide SCHEMBL42156 | 0.75 | — | — | |
| SCHEMBL968846 | 0.75 | — | — | |
| SCHEMBL311348 | 0.75 | — | — | |
| Water SCHEMBL10375906 | 0.75 | — | — | |
| Fluoride Ion SCHEMBL150863 | 0.75 | — | — | |
| SCHEMBL154041 | 0.67 | — | — | |
| SCHEMBL9039269 | 0.61 | — | — | |
| SCHEMBL9059043 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517895-B2 | Synthetic diazonamides | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1770093-A1 | Pyrido¬2,3-d|pyrimidine derivatives as phosphodiesterase inhibitors | Roche Palo Alto LLC (US) | 2007-04-04 | — | — | EP | disclosed |
| US-20060089397-A1 | Synthetic diazonamides | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-04-27 | — | — | US | disclosed |
| US-7022720-B2 | Synthetic diazonamides as novel anti-mitotic agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-04-04 | — | — | US | disclosed |
| US-20030100589-A1 | Synthetic diazonamides as novel anti-mitotic agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-05-29 | — | — | US | disclosed |
| EP-0631580-A1 | PYRIDO 2,3-d]PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-01-04 | — | — | EP | disclosed |
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993019068-A1 | PYRIDO[2,3-d]PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-09-30 | — | — | WO | disclosed |