Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL42156 | 0.75 | — | — | |
| SCHEMBL968846 | 0.75 | — | — | |
| Fluoride Ion SCHEMBL150863 | 0.75 | — | — | |
| SCHEMBL311348 | 0.75 | — | — | |
| Iodide SCHEMBL1686563 | 0.75 | — | — | |
| SCHEMBL3867733 | 0.75 | — | — | |
| SCHEMBL154041 | 0.67 | — | — | |
| SCHEMBL6692209 | 0.58 | — | — | |
| SCHEMBL8840579 | 0.50 | — | — | |
| SCHEMBL798394 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699114-B | Peptide having skin whitening activity and use thereof | 凯尔格恩有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109152718-B | Peptide having skin whitening activity and use thereof | 凯尔格恩有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111514197-A | Sobering-up composition and preparation method thereof | 京邦新药株式会社 | 2020-08-11 | — | — | CN | disclosed |
| CN-109952111-B | Pharmaceutical composition for preventing or treating alopecia comprising eremochloa ophiuroides extract or its isolate as active ingredient | 韩国原子力研究院 | 2020-06-02 | — | — | CN | disclosed |
| CN-110461864-A | With the peptide of cytoprotective effect and application thereof for resisting environmental pollutants | CAREGEN CO LTD | 2019-11-15 | — | — | CN | disclosed |
| CN-106420404-B | Fermenting plant grease cosmetic composition with antioxidant effect | 科丝美诗(中国)化妆品有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-110090168-A | It is a kind of have effects that hair growing wash shield product | 浙江立恩生物科技有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-110090170-A | Biological polyoses and its application with hair growing anticreep | 浙江立恩生物科技有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-106536542-B | Have effects that improve hypopigmentation and inhibit Adipogenesis peptide and its purposes | 凯尔格恩有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109790500-A | The composition for being used to improve skin comprising pearl fermentation material | 泉标食品有限公司 | 2019-05-21 | — | — | CN | disclosed |
| EP-0068259-A1 | Derivatives of substituted 2-amino-pyridine, process for their preparation, their use in medicaments and preparation thereof | BAYER AG (DE) | 1983-01-05 | — | — | EP | disclosed |
| EP-0053767-A1 | Tricyclic cytosine derivatives for use in pharmaceutical preparations and process for their preparation | BAYER AG (DE) | 1982-06-16 | — | — | EP | disclosed |
| EP-0049538-A2 | Use of thioureum derivatives as medicaments in the treatment of lipoid metabolism diseases | BAYER AG (DE) | 1982-04-14 | — | — | EP | disclosed |
| EP-0004624-B1 | CHROMANON DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES AND GROWTH-PROMOTING AGENTS | BAYER AG (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0030343-A1 | Substituted 2-amino-3,4-dihydropyridine derivatives, their preparation and use as medicaments | BAYER AG (DE) | 1981-06-17 | — | — | EP | disclosed |
| EP-0028765-A1 | Alkyl-urea derivatives for the treatment of lipometabolic diseases; process for their preparation, their use in medicaments for the treatment of lipometabolic disorders, medicaments containing them, process for the preparation of the medicaments, and some alkyl-urea derivatives | BAYER AG (DE) | 1981-05-20 | — | — | EP | disclosed |
| EP-0022958-A1 | Urea derivatives for use in the treatment of fat metabolism disorders | BAYER AG (DE) | 1981-01-28 | — | — | EP | disclosed |
| EP-0011237-A1 | Polyether derivatives, a method for their preparation and their use as pharmaceuticals | BAYER AG (DE) | 1980-05-28 | — | — | EP | disclosed |
| EP-0004624-A2 | Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |
| EP-0000704-A1 | Polyethers; process for their preparation and their use as lipid absorption inhibitors | BAYER AG (DE) | 1979-02-21 | — | — | EP | disclosed |