SCHEMBL386804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL391808	0.84	PDPK1 (0.57)	RAB9ASMN1; SMN2KDM4ECYP1A2NPC1
	SCHEMBL390356	0.82	PDPK1 (0.42)	RAB9ASMN1; SMN2KDM4ELMNACYP1A2
	SCHEMBL390245	0.77	HDAC6 (0.46)	RAB9ASMN1; SMN2KDM4ECHEK1NPC1
	SCHEMBL392148	0.76	ROCK1 (0.47)	RAB9ASMN1; SMN2KDM4ENPC1PDPK1
	SCHEMBL1144530	0.76	RAB9A (0.50)	RAB9ASMN1; SMN2KDM4ELMNACYP1A1
	SCHEMBL390192	0.76	KDM4E (0.47)	RAB9ASMN1; SMN2KDM4ELMNANPC1
	SCHEMBL21963465	0.75	RAB9A (0.40)	RAB9ASMN1; SMN2KDM4ELMNACYP1A1
	SCHEMBL4208111	0.73	RAB9A (0.74)	RAB9ASMN1; SMN2KDM4ELMNANPC1
	SCHEMBL389801	0.73	STK17B (0.43)	RAB9ASMN1; SMN2KDM4ELMNANPC1
	SCHEMBL2582411	0.71	ALDH1A1 (0.44)	RAB9ASMN1; SMN2KDM4ELMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.