Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426013 | 0.83 | LMNA (0.44) | L3MBTL1LMNASMN1; SMN2GAAHSP90AA1 | |
| SCHEMBL10877348 | 0.81 | LMNA (0.48) | L3MBTL1LMNASMN1; SMN2GAASLC40A1 | |
| SCHEMBL4425369 | 0.80 | LMNA (0.41) | L3MBTL1LMNASMN1; SMN2GAAHSP90AA1 | |
| SCHEMBL365374 | 0.74 | DYRK1A (0.50) | L3MBTL1LMNASMN1; SMN2GAASLC40A1 | |
| SCHEMBL168947 | 0.73 | KDM4E (0.62) | L3MBTL1LMNASMN1; SMN2GAAMETAP2 | |
| SCHEMBL744645 | 0.73 | ALDH1A1 (0.53) | L3MBTL1LMNASMN1; SMN2SLC40A1PDE4D | |
| SCHEMBL12996132 | 0.72 | KDM4E (0.52) | L3MBTL1LMNASMN1; SMN2GAASLC40A1 | |
| SCHEMBL10545410 | 0.70 | PARP1 (0.42) | L3MBTL1LMNASMN1; SMN2GAASLC40A1 | |
| SCHEMBL1831195 | 0.69 | KDM4E (0.39) | L3MBTL1SMN1; SMN2GAAHSP90AA1MEN1 | |
| SCHEMBL364531 | 0.69 | KDM4E (0.57) | L3MBTL1LMNASMN1; SMN2SLC40A1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2052604-A1 | Salts of 2-lodo-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl] benzol sulphonamide, method for its manufacture and its application as herbicide and plant growth regulator | Bayer CropScience AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| EP-1925203-A1 | Herbicidal combinations comprising amidosulfuron and a pyridine-herbicide | Bayer CropScience AG (DE) | 2008-05-28 | — | — | EP | disclosed |