Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868192 | 0.81 | L3MBTL1 (0.45) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL3415803 | 0.79 | LMNA (0.71) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL365374 | 0.78 | DYRK1A (0.50) | LMNAL3MBTL1GAASMN1; SMN2SLC40A1 | |
| SCHEMBL744645 | 0.76 | ALDH1A1 (0.53) | LMNAL3MBTL1SMN1; SMN2SLC40A1MEN1 | |
| SCHEMBL12996132 | 0.75 | KDM4E (0.52) | LMNAL3MBTL1GAASMN1; SMN2SLC40A1 | |
| SCHEMBL4426013 | 0.73 | LMNA (0.44) | LMNAL3MBTL1GAASMN1; SMN2HSP90AA1 | |
| SCHEMBL377229 | 0.72 | LMNA (0.50) | LMNAL3MBTL1SMN1; SMN2METAP2METAP1 | |
| SCHEMBL364531 | 0.72 | KDM4E (0.57) | LMNAL3MBTL1SMN1; SMN2METAP2METAP1 | |
| SCHEMBL5178813 | 0.72 | SMN1; SMN2 (0.53) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL24338474 | 0.72 | KDM4E (0.50) | L3MBTL1SLC40A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085182-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE MONOCARBOXYLIC ACID | BASF Aktiengesellschaft (DE) | 1986-04-23 | — | — | EP | disclosed |
| EP-0085182-A2 | Process for the preparation of quinoline monocarboxylic acid | BASF Aktiengesellschaft (DE) | 1983-08-10 | — | — | EP | disclosed |