Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868776 | 0.97 | KDM4E (0.35) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL3873493 | 0.93 | KDM4E (0.37) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL3868601 | 0.84 | GNRHR (0.39) | KDM4EHSD17B10MAPTPOLBMEN1 | |
| SCHEMBL17838804 | 0.84 | GNRHR (0.39) | KDM4EHSD17B10MAPTPOLBMEN1 | |
| SCHEMBL15624033 | 0.81 | MEN1 (0.36) | MAPTPOLBMEN1KDM4ATHRB | |
| SCHEMBL3867447 | 0.81 | GNRHR (0.38) | KDM4EHSD17B10MAPTPOLBMEN1 | |
| SCHEMBL5268112 | 0.79 | MAPT (0.41) | HPGDMAPTPOLBMEN1KDM4A | |
| SCHEMBL4591369 | 0.78 | DRD2 (0.38) | HPGDHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL29738288 | 0.78 | DRD2 (0.38) | HPGDHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL6018477 | 0.78 | MEN1 (0.35) | MAPTALDH1A1POLBMEN1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281405-B1 | Short-chained peptide-dye conjugates as contrast agents for optical diagnosis | DIAGNOSTIKFORSCHUNG INST (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-7175953-B2 | Short-warp peptide-dye conjugate as contrast agent for optical diagnostic | INSTITUTE FUER DIAGNOSTIK FORSCHUNG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-20060036072-A1 | Short-warp peptide dye conjugate as contrast agent for optical diagnostic | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2006-02-16 | — | — | US | disclosed |
| EP-1176987-B1 | SHORT-CHAIN PEPTIDE DYE CONJUGATES USED AS CONTRAST AGENTS FOR OPTICAL DIAGNOSTICS | DIAGNOSTIKFORSCHUNG INST (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6630570-B1 | Of tumor cells and tissues; derived from vaso-active intestinal protein, somatostatin or neurotensin; methine/cyanine; useful for endoscopy | Insitut für Diagnostikforschung GmbH (DE) | 2003-10-07 | — | — | US | disclosed |
| EP-1281405-A2 | Short-chained peptide-dye conjugates as contrast agents for optical diagnosis | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036072-A1 | Short-warp peptide dye conjugate as contrast agent for optical diagnostic | VIP, VASP, IAPP | KDM4E 4501/4885HPGD 2359/4885HSD17B10 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.