Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867447 | 0.91 | GNRHR (0.38) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL17838804 | 0.87 | GNRHR (0.39) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL3868601 | 0.87 | GNRHR (0.39) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL6018477 | 0.84 | MEN1 (0.35) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL15624013 | 0.84 | MAPT (0.35) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL3877741 | 0.82 | GNRHR (0.40) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL3868776 | 0.82 | KDM4E (0.35) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL3878105 | 0.81 | DRD2 (0.38) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL15624033 | 0.80 | MEN1 (0.36) | MAPTMEN1KDM4APOLBTHRB | |
| SCHEMBL2677869 | 0.80 | MEN1 (0.36) | MAPTMEN1KDM4APOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988060-B1 | ACID-LABILE AND ENZYMATICALLY DIVISIBLE DYE COMPOUNDS FOR DIAGNOSIS WITH NEAR INFRARED LIGHT AND FOR THERAPY | DIAGNOSTIKFORSCHUNG INST (DE) | 2007-06-13 | — | — | EP | disclosed |
| US-6534041-B1 | Having little or no fluorescence emission until dye is cleaved from construct at tumor or inflammation target site | INSTITUTE FOR DIAGNOSTIC RESEARCH GMBH OF THE FREE UNIVERSITY OF BERLIN (DE) | 2003-03-18 | — | — | US | disclosed |