Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868601 | 1.00 | GNRHR (0.39) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL3867447 | 0.97 | GNRHR (0.38) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL3877741 | 0.93 | GNRHR (0.40) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL5268112 | 0.87 | MAPT (0.41) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL3868705 | 0.84 | KDM4E (0.36) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL2677869 | 0.83 | MEN1 (0.36) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL28246187 | 0.83 | RARB (0.45) | POLBMEN1KDM4AMAPTTHRB | |
| SCHEMBL15624033 | 0.83 | MEN1 (0.36) | GNRHRPOLBMEN1KDM4AMAPT | |
| SCHEMBL29625553 | 0.83 | RARB (0.45) | POLBMEN1KDM4AMAPTTHRB | |
| Iodide SCHEMBL515607 | 0.82 | RARB (0.44) | POLBMEN1KDM4AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176819-A1 | ASYMMETRICALLY CHARGED NIR FLUOROPHORES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176819-A1 | ASYMMETRICALLY CHARGED NIR FLUOROPHORES | CRY2, PARP15, CRY1 | GNRHR 3252/4885POLB 3553/4885MEN1 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.