Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943574 | 0.83 | IDO1 (0.47) | IDO1TYRPYCR1 | |
| SCHEMBL11221907 | 0.79 | ADRB2 (0.45) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL17497706 | 0.79 | TSHR (0.36) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL11139354 | 0.76 | CYP3A4 (0.42) | CYP2C9ESR1TSHRESR2 | |
| SCHEMBL8023647 | 0.76 | PGK1 (0.36) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL2702724 | 0.74 | PTGS1 (0.47) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL6810356 | 0.72 | ESR1 (0.32) | PTGS2AKR1C3ESR1AKR1C2ESR2 | |
| SCHEMBL24507350 | 0.71 | FAAH (0.36) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL98942 | 0.70 | CYP2A6 (0.48) | IDO1PYCR1 | |
| SCHEMBL910708 | 0.70 | TAAR1 (0.48) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420187-B2 | Cellulose acylate composition, cellulose acylate film, and its applications | FUJIFILM CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20090082557-A1 | CELLULOSE ACYLATE FILM AND ITS APPLICATIONS | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20090002605-A1 | CELLULOSE ACYLATE COMPOSITION, CELLULOSE ACYLATE FILM, AND ITS APPLICATIONS | FUJIFILM CORPORATION (JP) | 2009-01-01 | — | — | US | disclosed |
| US-4546106-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4355034-A | Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents | MERCK & CO., INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212976-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4057637-A | RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-3971797-A | ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |