Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871435 | 0.84 | OPRL1 (0.68) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3868222 | 0.80 | OPRM1 (0.56) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3869853 | 0.75 | OPRM1 (0.59) | OPRM1OPRK1OPRL1 | |
| SCHEMBL2675276 | 0.75 | OPRM1 (0.70) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3872192 | 0.74 | OPRL1 (0.59) | OPRM1OPRK1OPRL1 | |
| SCHEMBL9841118 | 0.74 | OPRM1 (0.61) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3970762 | 0.74 | OPRL1 (0.64) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3878013 | 0.74 | OPRM1 (0.80) | OPRM1OPRK1OPRL1 | |
| SCHEMBL27597318 | 0.74 | OPRM1 (0.58) | OPRM1OPRK1OPRL1 | |
| SCHEMBL1939200 | 0.73 | AKT1 (0.63) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563809-B2 | Nociceptin analogs | PURDUE PHARMA, L.P. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20050148580-A1 | Nociceptin analogs | PURDUE PHARMA L.P | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148580-A1 | Nociceptin analogs | OPRL1, OPRK1, NPBWR1 | OPRM1 4/4885OPRK1 2/4885OPRL1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.