Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867779 | 0.90 | KDM4E (0.37) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL3867937 | 0.84 | HPGD (0.38) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL3866685 | 0.80 | SMYD3 (0.39) | — | |
| SCHEMBL3867446 | 0.78 | TDP1 (0.39) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL5268110 | 0.78 | MEN1 (0.39) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL17085345 | 0.78 | PTPN1 (0.58) | PTPN1 | |
| SCHEMBL22664055 | 0.75 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL3868600 | 0.75 | TDP1 (0.40) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL12146331 | 0.74 | MEN1 (0.56) | PTPN1MEN1LMNAMAPTTHRB | |
| SCHEMBL3859355 | 0.72 | MEN1 (0.41) | PTPN1MEN1LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281405-B1 | Short-chained peptide-dye conjugates as contrast agents for optical diagnosis | DIAGNOSTIKFORSCHUNG INST (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-7175953-B2 | Short-warp peptide-dye conjugate as contrast agent for optical diagnostic | INSTITUTE FUER DIAGNOSTIK FORSCHUNG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-20060036072-A1 | Short-warp peptide dye conjugate as contrast agent for optical diagnostic | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2006-02-16 | — | — | US | disclosed |
| EP-1176987-B1 | SHORT-CHAIN PEPTIDE DYE CONJUGATES USED AS CONTRAST AGENTS FOR OPTICAL DIAGNOSTICS | DIAGNOSTIKFORSCHUNG INST (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6630570-B1 | Of tumor cells and tissues; derived from vaso-active intestinal protein, somatostatin or neurotensin; methine/cyanine; useful for endoscopy | Insitut für Diagnostikforschung GmbH (DE) | 2003-10-07 | — | — | US | disclosed |
| EP-1281405-A2 | Short-chained peptide-dye conjugates as contrast agents for optical diagnosis | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036072-A1 | Short-warp peptide dye conjugate as contrast agent for optical diagnostic | VIP, VASP, IAPP | PTPN1 2742/4885MEN1 136/4885LMNA 3818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.