Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203029 | 0.73 | SLC6A2 (0.41) | KDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL10077963 | 0.70 | DRD4 (0.48) | ADRA1APROKR1SIGMAR1DRD4 | |
| SCHEMBL2199708 | 0.70 | HTR2C (0.41) | ADRA1ATSHRRIPK1DRD2DRD3 | |
| SCHEMBL6648965 | 0.65 | CYP1A2 (0.38) | CYP1A2 | |
| SCHEMBL5983948 | 0.65 | SLC6A3 (0.37) | — | |
| SCHEMBL10999017 | 0.65 | HRH3 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4HRH4 | |
| SCHEMBL23323166 | 0.65 | CHRNB2 (0.53) | DRD2 | |
| SCHEMBL11571755 | 0.64 | TSHR (0.42) | ADRA1AKDM4EALDH1A1TSHRRIPK1 | |
| SCHEMBL5139019 | 0.64 | USP30 (0.46) | KDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL6155692 | 0.63 | HRH4 (0.42) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473695-B2 | 4-imidazolin-2-one compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |