Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692495 | 0.84 | CYP1A2 (0.45) | ALDH1A1CYP3A4PTGS1PTGS2KMT2A | |
| SCHEMBL27901034 | 0.83 | LTB4R (0.47) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL5692490 | 0.82 | KMT2A (0.52) | POLBBCHEPTGS1PTGS2KMT2A | |
| SCHEMBL28006163 | 0.81 | FFAR1 (0.47) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL13168119 | 0.81 | POLB (0.42) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL28115672 | 0.81 | ALDH1A1 (0.51) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL28532192 | 0.80 | ALDH1A1 (0.45) | ALDH1A1RAB9ACYP3A4CYP2C19POLB | |
| SCHEMBL27455457 | 0.80 | LTB4R (0.45) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL23027267 | 0.79 | LTB4R (0.54) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL13572924 | 0.79 | LTB4R (0.54) | LTB4RLTB4R2HPGDALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638505-A4 | AMPHIPHILIC PYRIDINIUM COMPOUNDS, METHOD OF MAKING AND USE THEREOF | JACKSON H M FOUND MILITARY MED (US) | 2009-01-07 | — | — | EP | disclosed |
| EP-1638505-A2 | AMPHIPHILIC PYRIDINIUM COMPOUNDS, METHOD OF MAKING AND USE THEREOF | HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005002519-A2 | AMPHIPHILIC PYRIDINIUM COMPOUNDS, METHOD OF MAKING AND USE THEREOF | HENRY M.JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2005-01-13 | — | — | WO | disclosed |