Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572924 | 1.00 | LTB4R (0.54) | LTB4RLTB4R2ALDH1A1TSHRHPGD | |
| SCHEMBL563306 | 1.00 | LTB4R (0.54) | LTB4RLTB4R2ALDH1A1TSHRHPGD | |
| SCHEMBL20573131 | 0.89 | NPC1 (0.52) | LTB4RLTB4R2ALDH1A1TSHRHPGD | |
| SCHEMBL28115672 | 0.87 | ALDH1A1 (0.51) | LTB4RLTB4R2ALDH1A1HPGDRAB9A | |
| SCHEMBL12883167 | 0.86 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1TSHRMEN1 | |
| SCHEMBL21199753 | 0.86 | ALDH1A1 (0.50) | LTB4RLTB4R2ALDH1A1TSHRHPGD | |
| SCHEMBL12883163 | 0.86 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1TSHRMEN1 | |
| SCHEMBL12883164 | 0.86 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1TSHRMEN1 | |
| SCHEMBL5828002 | 0.85 | ALDH1A1 (0.48) | LTB4RLTB4R2ALDH1A1TSHRHPGD | |
| SCHEMBL7178642 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | LTB4R 4196/4885LTB4R2 4125/4885ALDH1A1 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.