Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124800 | 0.76 | PRCP (0.42) | — | |
| SCHEMBL28615303 | 0.76 | PRCP (0.42) | — | |
| SCHEMBL6176951 | 0.76 | CHRNB2 (0.47) | POLBSMN1; SMN2 | |
| SCHEMBL6176949 | 0.76 | CHRNB2 (0.47) | POLBSMN1; SMN2 | |
| SCHEMBL7012875 | 0.74 | MEN1 (0.49) | POLBSMN1; SMN2 | |
| SCHEMBL3014722 | 0.74 | PARP1 (0.31) | ALDH1A1POLBSMN1; SMN2HCAR2PKM | |
| SCHEMBL9474429 | 0.74 | CHRNB2 (0.49) | ALDH1A1POLBSMN1; SMN2HCAR2PKM | |
| SCHEMBL9362322 | 0.73 | MEN1 (0.47) | POLBSMN1; SMN2 | |
| SCHEMBL5842327 | 0.72 | RECQL (0.41) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8204301 | 0.70 | ALDH1A1 (0.36) | ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601726-B2 | Substituted pyrazolo[3,4-d]pyrimidines as p38 MAP kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2009-10-13 | — | — | US | disclosed |