SCHEMBL3872267

SCHEMBL3872267

O=C1CCC(COC(=O)C2CC3C=CC2C3)O1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.42
HSD17B10 Q99714 2/20 0.42
APEX1 P27695 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
ESR2 Q92731 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 10/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 1/20 0.41
HPGD P15428 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
LMNA P02545 3/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4911491 0.79 TP53 (0.54) POLBHSD17B10APEX1RECQLBLM
SCHEMBL3872277 0.77 ALDH1A1 (0.44) POLBHSD17B10APEX1RECQLBLM
SCHEMBL24255312 0.76 ALDH1A1 (0.46) POLBHSD17B10APEX1RECQLBLM
SCHEMBL3873465 0.74 ALDH1A1 (0.40) POLBHSD17B10APEX1RECQLBLM
SCHEMBL6830364 0.74 TP53 (0.44) POLBHSD17B10APEX1RECQLBLM
SCHEMBL417020 0.73 ALDH1A1 (0.46) POLBHSD17B10APEX1RECQLBLM
SCHEMBL19708550 0.73 ALDH1A1 (0.46) POLBHSD17B10APEX1RECQLBLM
SCHEMBL21895659 0.72 ALDH1A1 (0.43) POLBHSD17B10APEX1RECQLBLM
SCHEMBL6831517 0.72 CYP1A2 (0.43) TDP1ALDH1A1KMT2AKDM4EMEN1
SCHEMBL13897067 0.72 ALDH1A1 (0.53) POLBHSD17B10APEX1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521169-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-04-21 US disclosed
US-20060234153-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-19 US disclosed
EP-1557718-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-07-27 EP disclosed