Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808873 | 0.99 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL3221173 | 0.97 | OPRD1 (0.43) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL6367826 | 0.89 | OPRM1 (0.44) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL6367814 | 0.89 | OPRM1 (0.44) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL8017457 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL1674750 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL1674751 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL15757059 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL19967700 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL18613505 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040758-A2 | BIORESPONSIVE POLYMERS | Interface Biologics Inc. (CA) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008053362-A2 | BIORESPONSIVE POLYMERS | INTERFACE BIOLOGICS, INC. (CA) | 2008-05-08 | — | — | WO | disclosed |