Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL15486105 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL14631040 | 1.00 | TSHR (0.43) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methyl Alcohol SCHEMBL1303760 | 1.00 | TSHR (0.43) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methyl Alcohol SCHEMBL2938777 | 1.00 | — | — | |
| SCHEMBL949 | 0.91 | — | — | |
| Methylene Chloride SCHEMBL8405127 | 0.89 | TSHR (0.42) | TSHRTDP1TP53ALDH1A1 | |
| Methylamine SCHEMBL7494882 | 0.87 | — | — | |
| Alcohol SCHEMBL7158313 | 0.87 | — | — | |
| Water SCHEMBL4995754 | 0.86 | — | — | |
| SCHEMBL8157042 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099456-A2 | N-OXIDES OF 4,5-EPOXY-MORPHINANIUM ANALOGS | Progenics Pharmaceuticals, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009067275-A1 | N-OXIDES OF 4,5-EPOXY-MORPHINANIUM ANALOGS | PROGENICS PHARMACEUTICALS, INC (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20080234306-A1 | N-Oxides of 4,5-Epoxy-Morphinanium Analogs | PROGENICS PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| WO-2008070462-A2 | N-OXIDES OF 4,5-EPOXY-MORPHINANIUM ANALOGS | PROGENICS PHARMACEUTICALS, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| EP-0979244-B1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-03-02 | — | — | EP | disclosed |
| US-6683095-B2 | ANTICARCINOGENIC AGENTS; ANTIPROLIFERATION AGENTS | LG LIFE SCIENCES LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | LG LIFE SCIENCES LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
| EP-1280789-A1 | CDK INHIBITORS HAVING 3-HYDROXYCHROMEN-4-ONE STRUCTURE | LG Life Sciences Ltd. (KR) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001083469-A1 | CDK INHIBITORS HAVING 3-HYDROXYCHROMEN-4-ONE STRUCTURE | LG LIFE SCIENCES LTD. (KR) | 2001-11-08 | — | — | WO | disclosed |
| EP-0979244-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049193-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | CDK4, CDK3, CDK6 | TSHR 4555/4885TDP1 2335/4885TP53 453/4885 |
| US-20080234306-A1 | N-Oxides of 4,5-Epoxy-Morphinanium Analogs | OPRM1, OPRD1, OPRK1 | TSHR 1793/4885TDP1 3929/4885TP53 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.