Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221143 | 1.00 | CA2 (0.35) | CA2MAPK1PTPN1ACP1CDC25B | |
| SCHEMBL7422145 | 0.70 | GRIK1 (0.40) | — | |
| SCHEMBL5376939 | 0.70 | CA2 (0.32) | CA2MAPK1 | |
| SCHEMBL4978274 | 0.63 | CA2 (0.47) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8775616 | 0.63 | PTPN1 (0.44) | PTPN1ACP1CDC25BDAGLAGLS | |
| SCHEMBL13477900 | 0.63 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11191261 | 0.62 | PPARG (0.42) | PTPN1ACP1CDC25BHSD17B10GPR84 | |
| SCHEMBL9722690 | 0.62 | CA2 (0.41) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL407615 | 0.60 | CA2 (0.44) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1527354 | 0.60 | CA2 (0.44) | CA2MAPK1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612059-B2 | Pyrrolidine bicyclic compounds and its derivatives, compositions and methods of use | VICURON PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612059-B2 | Pyrrolidine bicyclic compounds and its derivatives, compositions and methods of use | VICURON PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090149509-A1 | NOVEL PYRROLIDINE BICYCLIC COMPOUNDS AND ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE | VICURON PHARMACEUTICALS INC. (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090149509-A1 | NOVEL PYRROLIDINE BICYCLIC COMPOUNDS AND ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE | VICURON PHARMACEUTICALS INC. (US) | 2009-06-11 | — | — | US | disclosed |
| EP-1771421-B1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | SERONO LAB (CH) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149509-A1 | NOVEL PYRROLIDINE BICYCLIC COMPOUNDS AND ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE | PDF, PNPO, PDXK | CA2 4872/4885MAPK1 1844/4885PTPN1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.