Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871581 | 0.92 | AGTR2 (0.41) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL3945157 | 0.90 | AGTR1 (0.46) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL17671294 | 0.77 | AGTR2 (0.48) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083906 | 0.75 | AGTR1 (0.47) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL22533557 | 0.74 | AGTR2 (0.51) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL3176403 | 0.73 | AGTR2 (0.52) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL3977106 | 0.71 | AGTR2 (0.62) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL21168140 | 0.69 | AGTR2 (0.59) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL30206864 | 0.69 | PPARG (0.59) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL7018017 | 0.69 | PPARG (0.59) | AGTR1AGTR2CYP3A4ADORA3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833801-B9 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2009-02-25 | — | — | EP | claimed |
| EP-1833801-B1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2008-06-04 | — | — | EP | claimed |
| EP-1833801-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA, S.L (ES) | 2007-09-19 | — | — | EP | claimed |
| WO-2006067215-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUÍMICA, S. L. (ES) | 2006-06-29 | — | — | WO | claimed |
| EP-1833801-B9 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2009-02-25 | — | — | EP | disclosed |
| EP-1833801-B1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2008-06-04 | — | — | EP | disclosed |
| EP-1833801-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA, S.L (ES) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006067215-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUÍMICA, S. L. (ES) | 2006-06-29 | — | — | WO | disclosed |