Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871581 | 0.90 | AGTR2 (0.41) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL3873328 | 0.90 | AGTR1 (0.38) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL17671294 | 0.74 | AGTR2 (0.48) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL5319554 | 0.74 | AGTR1 (0.52) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL6866628 | 0.73 | DHODH (0.54) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL22533560 | 0.72 | AGTR1 (0.62) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL25963850 | 0.72 | AGTR1 (0.48) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL8265591 | 0.72 | AGTR1 (0.64) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL30206716 | 0.71 | AGTR1 (0.48) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL21125116 | 0.70 | AGTR1 (0.47) | AGTR1ABCB11EGFRERBB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833801-B9 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2009-02-25 | — | — | EP | claimed |
| EP-1833801-B1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2008-06-04 | — | — | EP | claimed |