Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815268 | 0.79 | HRH3 (0.41) | HRH1RAB9ASMN1; SMN2MAPTLIN28A | |
| SCHEMBL8670245 | 0.73 | MEN1 (0.54) | HRH1RAB9ASMN1; SMN2MAPTLIN28A | |
| SCHEMBL9514491 | 0.73 | ALDH1A1 (0.46) | HRH1RAB9ASMN1; SMN2MAPTLIN28A | |
| SCHEMBL5066306 | 0.72 | HRH1 (0.52) | HRH1RAB9ASMN1; SMN2MAPTLIN28A | |
| SCHEMBL8304763 | 0.71 | NPC1 (0.42) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL4128400 | 0.71 | NFE2L2 (0.50) | NFE2L2TDP1 | |
| SCHEMBL8112257 | 0.71 | NFE2L2 (0.50) | NFE2L2ALDH1A1 | |
| SCHEMBL6006628 | 0.70 | — | — | |
| SCHEMBL945880 | 0.69 | — | — | |
| SCHEMBL5643529 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473695-B2 | 4-imidazolin-2-one compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |