Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874849 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL223591 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL223592 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| Benzene SCHEMBL10426584 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL18779752 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL5569513 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL6259235 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL5541980 | 0.75 | CYP2D6 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL27647042 | 0.75 | KMT2A (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL5541983 | 0.75 | CYP2D6 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040099975-A1 | Method of preparing a surface modifier for nanoparticles, surface-modified inorganic oxide nanoparticles, and applications thereof | FAR EASTERN TEXTILE LTD. | 2004-05-27 | — | — | US | claimed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| CN-101657414-A | Oxime compound, photosensitive composition, color filter, method for production of the color filter, and liquid crystal display element | FUJIFILM CORP JP | 2010-02-24 | — | — | CN | disclosed |
| EP-2116527-A1 | OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, METHOD FOR PRODUCTION OF THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT | FUJIFILM Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| CN-1508198-A | Preparation method of nano-scale particle surface modifier, nano inorganic oxide dispersion and application thereof | 远东纺织股份有限公司 | 2004-06-30 | — | — | CN | disclosed |
| US-20040099975-A1 | Method of preparing a surface modifier for nanoparticles, surface-modified inorganic oxide nanoparticles, and applications thereof | FAR EASTERN TEXTILE LTD. | 2004-05-27 | — | — | US | disclosed |
| US-20030129504-A1 | Photosensitive resin compositon, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof | FUJI PHOTO FILM CO., LTD. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | ALDH1A1 355/4885NPC1 2404/4885RAB9A 2824/4885 |
| US-20040099975-A1 | Method of preparing a surface modifier for nanoparticles, surface-modified inorganic oxide nanoparticles, and applications thereof | ADH1A, PCNA, SUMO1 | ALDH1A1 112/4885NPC1 2901/4885RAB9A 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.