SCHEMBL38760

SCHEMBL38760

Nc1cc(C=Cc2ccccc2)c(S(=O)(=O)O)c(S(=O)(=O)O)c1N.Nc1ccnnn1.Nc1ccnnn1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.31
PLAT P00750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38677 0.86 MAOB (0.39)
SCHEMBL11656752 0.84 MAOB (0.38)
SCHEMBL27554229 0.82 DAPK1 (0.32)
SCHEMBL38468 0.82 PLAU (0.33) PLAUPLAT
Tetrazole SCHEMBL11228500 0.79 CA2 (0.30)
SCHEMBL27418632 0.75 CYP19A1 (0.39) PLAUPLAT
SCHEMBL7516288 0.75 CYP19A1 (0.39)
SCHEMBL27815218 0.75 DHFR (0.35) PLAU
SCHEMBL10636487 0.74 MAOB (0.31)
SCHEMBL28977388 0.74 CYP19A1 (0.38) PLAUPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571973-B1 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2020-04-01 EP disclosed
US-8740997-B2 Optical brighteners and compositions comprising the same MILLIKEN & COMPANY (US) 2014-06-03 US disclosed
US-20130281347-A1 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2013-10-24 US disclosed
US-8454711-B2 Optical brighteners and compositions comprising the same MILLIKEN & COMPANY (US) 2013-06-04 US disclosed
EP-2571973-A2 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2013-03-27 EP disclosed
US-20120329699-A1 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2012-12-27 US disclosed
US-8262744-B2 Optical brighteners and compositions comprising the same MILLIKEN & COMPANY (US) 2012-09-11 US disclosed
WO-2011146604-A2 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2011-11-24 WO disclosed
US-20110287999-A1 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110287999-A1 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME DBN1, AOC1, RARB PLAU 1622/4885PLAT 674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.