SCHEMBL387611

SCHEMBL387611

CO[Si](C)(CCCC#N)OC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL385432 0.93 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL4201613 0.90 TSHR (0.36) TSHR
SCHEMBL19680572 0.86 TSHR (0.38) TSHR
SCHEMBL601626 0.85 ALDH1A1 (0.35) TSHRALDH1A1TDP1
SCHEMBL235280 0.81 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL10178707 0.80
SCHEMBL31338986 0.80 ALDH1A1 (0.32) ALDH1A1
SCHEMBL126260 0.78 TSHR (0.42) TSHRALDH1A1TDP1
SCHEMBL1584800 0.78 TSHR (0.42) TSHRALDH1A1TDP1
SCHEMBL914867 0.77 TSHR (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230360821-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE AMINDON INC. 2023-11-09 US claimed
US-11749422-B2 Silane functional stabilizers for extending long-term electrical power cable performance NOVINIUM, LLC (US) 2023-09-05 US claimed
CN-115322377-A Pre-condensed power cable insulation aging repair liquid and preparation method and application thereof 广东电网有限责任公司广州供电局 2022-11-11 CN claimed
EP-3972745-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE Novinium, Inc. (US) 2022-03-30 EP claimed
US-10923249-B2 Electroless plating of silver onto graphite Henkel IP & Holding GmbH (DE) 2021-02-16 US claimed
WO-2021011696-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE NOVINIUM, INC. (US) 2021-01-21 WO claimed
US-20210017384-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE MADISON ELECTRIC PRODUCTS, LLC 2021-01-21 US claimed
US-20190295747-A1 ELECTROLESS PLATING OF SILVER ONTO GRAPHITE HENKEL AG & CO. KGAA (DE) 2019-09-26 US claimed
US-10361016-B2 Electroless plating of silver onto graphite Henkel IP & Holding GmbH (DE) 2019-07-23 US claimed
EP-1782436-B1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM INC (US) 2017-05-31 EP claimed
EP-0987286-B1 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING (US) 2004-07-14 EP claimed
EP-1339727-A1 PROCESS FOR PREPARING PRIMARY AMINOORGANOSILANES Crompton Corporation (US) 2003-09-03 EP claimed
WO-2003044027-A1 PROCESS FOR PREPARING BIS(SILYLORGANO) AMINES GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO claimed
WO-2003027677-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-04-03 WO claimed
US-6417381-B1 HYDROGENATION OF CYANOORGANOSILANE USING RHODIUM, RUTHENIUM, PALLADIUM, OR PLATINUM CATALYST CROMPTON CORPORATION 2002-07-09 US claimed
WO-2002046202-A1 PROCESS FOR PREPARING PRIMARY AMINOORGANOSILANES CROMPTON CORPORATION (US) 2002-06-13 WO claimed
EP-0987286-A2 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-03-22 EP claimed
US-6013705-A Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-01-11 US claimed
US-5232982-A Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure GENERAL ELECTRIC COMPANY (US) 1993-08-03 US claimed
US-5213899-A ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-05-25 US claimed