Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730198 | 0.79 | PDE5A (0.40) | PDE5AIDO1RAB9AMAPTALDH1A1 | |
| SCHEMBL4380609 | 0.79 | GRM5 (0.45) | PDE5AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5585297 | 0.75 | PDE5A (0.38) | PDE5AALDH1A1SMN1; SMN2SLC6A2KDM4E | |
| SCHEMBL5585320 | 0.75 | PDE5A (0.38) | PDE5AALDH1A1SMN1; SMN2SLC6A2KDM4E | |
| SCHEMBL5585291 | 0.75 | PDE5A (0.38) | PDE5AALDH1A1SMN1; SMN2SLC6A2KDM4E | |
| SCHEMBL4726054 | 0.74 | ALDH1A1 (0.48) | PDE5AIDO1RAB9AMAPTALDH1A1 | |
| SCHEMBL4378934 | 0.74 | NFE2L2 (0.51) | PDE5ARAB9AMAPTALDH1A1LMNA | |
| SCHEMBL2485504 | 0.74 | MAPT (0.66) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4307757 | 0.73 | CHRNB2 (0.46) | PDE5AIDO1MAPTALDH1A1RECQL | |
| SCHEMBL91148 | 0.73 | S1PR4 (0.55) | PDE5AIDO1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009031105-A2 | NON-HOMOGENEOUS MODIFICATION OF LIQUIDS | KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) | 2009-03-12 | — | — | WO | disclosed |
| EP-2034028-A1 | Non-homogeneous modification of liquids | Koninklijke Philips Electronics N.V. (NL) | 2009-03-11 | — | — | EP | disclosed |