SCHEMBL387640

SCHEMBL387640

[CH]=CCCCCCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
HIF1A Q16665 3/20 0.34
EPAS1 Q99814 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29004281 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL17135371 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL1773307 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL3701351 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL17135372 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL17352702 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL387190 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL1245200 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL182183 1.00 LMNA (0.43) LMNAHIF1AEPAS1
SCHEMBL387225 1.00 LMNA (0.43) LMNAHIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229089-A1 A process for enzymatic synthesis of amides from amines and carboxylic acids or esters XP CHEMISTRIES AB (SE) 2024-07-11 US disclosed
CN-118139909-A Beta-methyl-delta-valerolactone based polymer 株式会社可乐丽 2024-06-04 CN disclosed
CN-118139926-A Resin composition 株式会社可乐丽 2024-06-04 CN disclosed
CN-117597449-A Method for the enzymatic synthesis of amides from amines and carboxylic acids or esterases XP化学有限公司 2024-02-23 CN disclosed
EP-4308714-A1 A PROCESS FOR ENZYMATIC SYNTHESIS OF AMIDES FROM AMINES AND CARBOXYLIC ACIDS OR ESTERS XP Chemistries AB (SE) 2024-01-24 EP disclosed
WO-2023225216-A1 FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF HOUSTON SYSTEM (US) 2023-11-23 WO disclosed
WO-2023068345-A1 Β-METHYL-δ-VALEROLACTONE POLYMER 株式会社クラレ 2023-04-27 WO disclosed
WO-2023068346-A1 Β-METHYL-δ-VALEROLACTONE POLYMER 株式会社クラレ 2023-04-27 WO disclosed
WO-2023068348-A1 RESIN COMPOSITION 株式会社クラレ 2023-04-27 WO disclosed
CN-103725652-B A kind of acyl-CoA synthetase and application thereof 无锡新和源发酵技术研究院有限公司 2016-06-29 CN disclosed
US-20070105933-A1 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-05-10 US disclosed
EP-1300405-B1 AMINO ALCOHOL DERIVATIVES SANKYO CO (JP) 2007-04-18 EP disclosed
US-7199150-B2 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-04-03 US disclosed
US-6964976-B2 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2005-11-15 US disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
US-20040132784-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-08 US disclosed
US-6723745-B2 PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL SANKYO COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030236297-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2003-12-25 US disclosed
EP-1300405-A1 AMINO ALCOHOL DERIVATIVES Sankyo Company, Limited (JP) 2003-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236297-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LMNA 3703/4885HIF1A 2134/4885EPAS1 2644/4885
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these PHOSPHO1, CD4, FCGRT LMNA 4143/4885HIF1A 1588/4885EPAS1 647/4885
US-20040132784-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LMNA 3703/4885HIF1A 2134/4885EPAS1 2644/4885
US-20070105933-A1 Amino alcohol compounds ADH1C, C9, SSB LMNA 1187/4885HIF1A 1275/4885EPAS1 784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.