SCHEMBL3876852

SCHEMBL3876852

CCCCOc1c(C)cc(S2(OS(=O)(=O)C(F)(F)F)CCCC2)cc1C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.32
THRB P10828 2/20 0.32
FFAR4 Q5NUL3 2/20 0.32
CYP3A4 P08684 1/20 0.31
KCNH2 Q12809 1/20 0.31
CACNA1C Q13936 1/20 0.31
SCN5A Q14524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3871483 0.88
SCHEMBL3873625 0.87 CA1 (0.31)
SCHEMBL7158788 0.84 SCN8A (0.34)
SCHEMBL3871386 0.84 CCNE2 (0.36)
SCHEMBL3150421 0.81 TSHR (0.41)
SCHEMBL3876693 0.81 THRA (0.31) THRATHRB
SCHEMBL3871345 0.80
SCHEMBL449173 0.79 CA12 (0.39)
SCHEMBL3878050 0.77 FAAH (0.32) KCNH2
SCHEMBL36290 0.71 KMT2A (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638261-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-12-29 US disclosed
US-20090148790-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2009-06-11 US disclosed
US-7521169-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-04-21 US disclosed
US-20060234153-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-19 US disclosed
EP-1557718-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-07-27 EP disclosed
US-20030219680-A1 Photoresists useful for microfabrication utilizing deep ultraviolet rays such as an excimer laser, x-rays such as synchrotron radiation, and electron beams JSR CORPORATION (JP) 2003-11-27 US disclosed