Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872126 | 0.88 | HSD17B1 (0.38) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL7127376 | 0.85 | ESR1 (0.43) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL3874329 | 0.82 | LMNA (0.47) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL6570677 | 0.77 | HSD17B1 (0.43) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL3873197 | 0.77 | LMNA (0.47) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL4370456 | 0.74 | LMNA (0.42) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL4370949 | 0.74 | HSD17B1 (0.36) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL3874456 | 0.74 | HSD17B1 (0.36) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL5973177 | 0.73 | LMNA (0.47) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL6572198 | 0.73 | LMNA (0.45) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291929-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. ORGANON (NL) | 2009-11-26 | — | — | US | disclosed |
| EP-1893630-B1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | ORGANON NV (NL) | 2009-09-02 | — | — | EP | disclosed |
| EP-1893630-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. Organon (NL) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134167-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. ORGANON (NL) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291929-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | NR5A1, AR, CYP17A1 | HSD17B1 18/4885LMNA 4054/4885MAPT 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.