Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877022 | 0.85 | HSD17B1 (0.39) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL14568941 | 0.84 | AKR1C3 (0.35) | ESR1OPRM1MAPTHSD11B1MTNR1A | |
| SCHEMBL6867122 | 0.84 | ESR1 (0.39) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL6467351 | 0.83 | ESR1 (0.52) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL9725122 | 0.83 | ESR1 (0.52) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL7026300 | 0.78 | ESR1 (0.41) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL9626575 | 0.78 | ESR1 (0.41) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL9190270 | 0.78 | ESR1 (0.54) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL3873197 | 0.76 | LMNA (0.47) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL3872126 | 0.73 | HSD17B1 (0.38) | ESR1LMNASMN1; SMN2PGRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053993-A1 | ANDROGENIC 14.ALPHA, 17.ALPHA-ETHENOSTEROIDS | AKZO NOBEL N.V. (NL) | 2003-07-03 | — | — | WO | disclosed |