Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656493 | 0.92 | ALDH1A1 (0.60) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| SCHEMBL8769925 | 0.90 | ALDH1A1 (0.61) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL11838297 | 0.90 | ALDH1A1 (0.58) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| SCHEMBL8769923 | 0.90 | ALDH1A1 (0.58) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| Water SCHEMBL8769949 | 0.89 | ALDH1A1 (0.59) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| SCHEMBL9188689 | 0.87 | ALDH1A1 (0.56) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| SCHEMBL38644 | 0.85 | SRD5A2 (0.60) | SRD5A2PLA2G4BPOLBMAPK1LMNA | |
| SCHEMBL16035699 | 0.85 | ALOX15 (0.65) | SRD5A2GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL17141840 | 0.84 | PLA2G4B (0.59) | PLA2G4BPOLBLMNAMAOBALDH1A1 | |
| SCHEMBL9189255 | 0.83 | PTGS2 (0.72) | PLA2G4BPOLBLMNAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426390-B2 | Triazene compounds for the treatment of cancer | TRIN THERAPEUTICS GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| US-8426390-B2 | Triazene compounds for the treatment of cancer | TRIN THERAPEUTICS GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20120028927-A1 | Novel Triazene Compounds For The Treatment Of Cancer | TRIN THERAPEUTICS GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20120028927-A1 | Novel Triazene Compounds For The Treatment Of Cancer | TRIN THERAPEUTICS GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028927-A1 | Novel Triazene Compounds For The Treatment Of Cancer | KRAS, TP53, VHL | SRD5A2 3680/4885PLA2G4B 3795/4885POLB 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.