Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SI | P14410 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333679 | 0.84 | SRD5A1 (0.61) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL18155873 | 0.82 | KDM4E (0.67) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL11079352 | 0.80 | GAA (0.63) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL11384270 | 0.80 | SRD5A1 (0.67) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL11440831 | 0.80 | GAA (0.59) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL8179535 | 0.79 | ALDH1A1 (0.67) | CA9KDM4EHSD17B10MAOBALDH1A1 | |
| SCHEMBL7001521 | 0.79 | MAOA (0.63) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL28542436 | 0.78 | ERN1 (0.78) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL11075633 | 0.76 | KDM4E (0.70) | CA9GAAKDM4EGLAHSD17B10 | |
| SCHEMBL8684228 | 0.76 | CA9 (0.50) | CA9GAAKDM4EGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527934-B2 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-05 | — | — | US | disclosed |
| US-7527934-B2 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-05 | — | — | US | disclosed |
| US-7527934-B2 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-05 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20060057658-A1 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-16 | — | — | US | disclosed |
| WO-2006025983-A2 | LABELED SUBSTRATE CONJUGATES FOR IDENTIFYING ENZYME INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-09 | — | — | WO | disclosed |
| US-4737517-A | Coumarin derivatives, pharmaceutical compositions containing the same, and the use thereof in the treatment of cancer | FIDIA, S.P.A. (IT) | 1988-04-12 | — | — | US | disclosed |
| EP-0133766-A2 | Coumarin derivatives, pharmaceutical compositions containing the same, and the use thereof in the treatment of cancer | FIDIA S.p.A. (IT) | 1985-03-06 | — | — | EP | disclosed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |
| US-4294847-A | 8-Aminoalkyl-4-alkylisopsoralens | THOMAS C. ELDER, INC. (US) | 1981-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | CA9 2007/4885GAA 67/4885KDM4E 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.