Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | SI | P14410 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079352 | 0.88 | GAA (0.63) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL6156306 | 0.84 | ESR1 (0.55) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL7001521 | 0.84 | MAOA (0.63) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL3878331 | 0.82 | CA9 (0.65) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL11440831 | 0.81 | GAA (0.59) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL14756049 | 0.81 | GAA (0.70) | KDM4EGAAALDH1A1MAOBMCL1 | |
| SCHEMBL4187220 | 0.80 | MAOB (1.00) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| 4-Methyldaphnetin SCHEMBL29671915 | 0.80 | MCL1 (1.00) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| 4-Methyldaphnetin SCHEMBL1065373 | 0.80 | MCL1 (1.00) | KDM4EGAAALDH1A1MAOBMAPK1 | |
| SCHEMBL109411 | 0.79 | ALDH1A1 (0.72) | KDM4EGAAALDH1A1MAOBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295053-B1 | Novel 2H-chromen-2-one-3-carboxamides for medical uses | INST MATERIA MEDICA CAMS (CN) | 2016-10-19 | — | — | EP | disclosed |