Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | FECH | P22830 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 9/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061909 | 0.93 | CHRNB2 (0.44) | CHRNB2CHRNA4MTORPIK3CDCSNK2A2 | |
| Trifluoroacetic Acid SCHEMBL3888334 | 0.90 | DPP4 (0.36) | DPP4FAPHRH4DPP9 | |
| Trifluoroacetic Acid SCHEMBL3874248 | 0.87 | DPP4 (0.43) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL3888649 | 0.86 | DPP4 (0.38) | CHRNB2CHRNA4DPP4FAPHRH4 | |
| Trifluoroacetic Acid SCHEMBL3874233 | 0.85 | DPP4 (0.39) | DPP4FAPRENHRH4DPP9 | |
| Trifluoroacetic Acid SCHEMBL3877495 | 0.85 | DPP4 (0.38) | DPP4FAPHRH4DPP9 | |
| Trifluoroacetic Acid SCHEMBL3875141 | 0.84 | DPP4 (0.37) | DPP4FAPHRH4DPP9 | |
| Trifluoroacetic Acid SCHEMBL3879283 | 0.82 | DPP4 (0.38) | DPP4FAPHRH4DPP9 | |
| SCHEMBL13866969 | 0.82 | DPP4 (0.41) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL3881735 | 0.82 | DPP4 (0.48) | DPP4FAPHRH4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | EISAI CO., LTD. (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1568699-A1 | 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND | Eisai Co., Ltd. (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | NR2C2, NR0B2, DPP4 | CHRNB2 526/4885CHRNA4 283/4885MTOR 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.