Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879326 | 0.86 | ALDH1A1 (0.35) | F10SIGMAR1ITGB3ITGA2BHTR4 | |
| SCHEMBL3885138 | 0.72 | HTR4 (0.33) | F10HTR4ALDH1A1 | |
| SCHEMBL25122577 | 0.69 | HRH3 (0.40) | SIGMAR1ITGB3ITGA2BHTR4ALDH1A1 | |
| SCHEMBL220468 | 0.69 | F10 (0.48) | F10SMYD3ALDH1A1 | |
| SCHEMBL13999390 | 0.68 | HRH3 (0.39) | HTR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10447140 | 0.67 | HRH3 (0.45) | HTR4 | |
| SCHEMBL31273027 | 0.67 | HRH3 (0.47) | HTR4ALDH1A1 | |
| SCHEMBL31272933 | 0.67 | HRH3 (0.47) | SIGMAR1HTR4ALDH1A1 | |
| Fumaric Acid SCHEMBL3873534 | 0.66 | F10 (0.47) | F10SMYD3ALDH1A1MAPT | |
| SCHEMBL20782485 | 0.66 | ENPP1 (0.43) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |