Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | ICOSLG | O75144 | 1/20 | 0.46 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957848 | 0.86 | HDAC1 (0.58) | MAPTSMN1; SMN2KDM4EHTTHDAC1 | |
| SCHEMBL3958683 | 0.85 | HDAC1 (0.53) | MAPTSMN1; SMN2KDM4EHDAC1ICOSLG | |
| SCHEMBL3955981 | 0.84 | ALDH1A1 (0.51) | MAPTSMN1; SMN2KDM4EHTTHDAC1 | |
| SCHEMBL3959328 | 0.84 | NPC1 (0.61) | MAPTKDM4EHDAC1RAB9A | |
| SCHEMBL3957764 | 0.83 | HDAC1 (0.56) | MAPTSMN1; SMN2KDM4EHDAC1ICOSLG | |
| SCHEMBL3959300 | 0.83 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2KDM4EHDAC1RAB9A | |
| SCHEMBL3879025 | 0.83 | LMNA (0.55) | MAPTSMN1; SMN2KDM4EHTTHDAC1 | |
| SCHEMBL3957756 | 0.82 | NPC1 (0.50) | MAPTSMN1; SMN2KDM4EHTTHDAC1 | |
| SCHEMBL3954526 | 0.82 | MEN1 (0.49) | MAPTSMN1; SMN2KDM4EHTTHDAC1 | |
| SCHEMBL3957834 | 0.82 | FAAH (0.58) | MAPTSMN1; SMN2HDAC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010150-A2 | STABLE EMULSION FORMULATIONS | Amgen Inc. (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007124465-A2 | STABLE EMULSION FORMULATIONS | AMGEN INC. (US) | 2007-11-01 | — | — | WO | claimed |
| EP-2079525-A1 | CALCIUM RECEPTOR MODULATING AGENTS | Amgen Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-2010150-A2 | STABLE EMULSION FORMULATIONS | Amgen Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2008057282-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2007124465-A2 | STABLE EMULSION FORMULATIONS | AMGEN INC. (US) | 2007-11-01 | — | — | WO | disclosed |