Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985060 | 0.84 | PGR (0.57) | PGRNR3C1 | |
| SCHEMBL3874234 | 0.81 | PGR (0.72) | PGRNR3C1 | |
| SCHEMBL3984839 | 0.77 | PGR (0.50) | PGRNR3C1 | |
| SCHEMBL3984725 | 0.74 | PGR (0.62) | PGRNR3C1 | |
| SCHEMBL3874025 | 0.74 | PGR (0.65) | PGRNR3C1 | |
| SCHEMBL3981683 | 0.73 | PGR (0.63) | PGRNR3C1 | |
| SCHEMBL3981829 | 0.72 | PGR (0.58) | PGRNR3C1 | |
| SCHEMBL3879414 | 0.71 | PGR (1.00) | PGRNR3C1 | |
| Tanaproget SCHEMBL62188 | 0.71 | PGR (1.00) | PGRNR3C1 | |
| SCHEMBL6397892 | 0.70 | PGR (0.65) | PGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329690-B2 | Cyclothiocarbamate derivatives as progesterone receptor modulators | WYETH LLC (US) | 2012-12-11 | — | — | US | claimed |
| US-20090281096-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2009-11-12 | — | — | US | claimed |
| US-7569564-B2 | Cyclothiocarbamate derivatives as progesterone receptor modulators | WYETH (US) | 2009-08-04 | — | — | US | claimed |
| EP-1175411-B1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH CORP (US) | 2008-02-20 | — | — | EP | claimed |
| US-7081457-B2 | Contraceptives; hormone replacement therapy | WYETH (US) | 2006-07-25 | — | — | US | claimed |
| US-20060142280-A1 | Such as 4-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1 ,3]oxazin-6-yl)-thiophene-2-carbonitrile; estrogen receptor agonists, progesterone receptor antagonists; hormone replacement therapy | WYETH (US) | 2006-06-29 | — | — | US | claimed |
| US-20030092711-A1 | Contraceptives; hormone replacement therapy | WYETH LLC | 2003-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142280-A1 | Such as 4-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1 ,3]oxazin-6-yl)-thiophene-2-carbonitrile; estrogen receptor agonists, progesterone receptor antagonists; hormone replacement therapy | PGR, ESR1, GPER1 | PGR 1/4885NR3C1 26/4885 |
| US-20090281096-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC2, PGRMC1 | PGR 1/4885NR3C1 17/4885 |
| US-20030092711-A1 | Contraceptives; hormone replacement therapy | PGR, GNRHR, GHRHR | PGR 1/4885NR3C1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.