Tanaproget

Tanaproget

SCHEMBL62188

Cn1c(C#N)ccc1-c1ccc2c(c1)C(C)(C)OC(=S)N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 1.00
NR3C1 P04150 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13579113 0.87 PGR (0.77) PGRNR3C1
SCHEMBL5519179 0.86 PGR (0.76) PGRNR3C1
SCHEMBL61743 0.86 PGR (1.00) PGRNR3C1
SCHEMBL5512567 0.85 PGR (0.74) PGRNR3C1
SCHEMBL3869144 0.85 PGR (0.77) PGRNR3C1
SCHEMBL4185522 0.85 PGR (0.98) PGRNR3C1
SCHEMBL3874234 0.84 PGR (0.72) PGRNR3C1
SCHEMBL5512561 0.84 PGR (0.72) PGRNR3C1
SCHEMBL5512888 0.84 PGR (0.72) PGRNR3C1
SCHEMBL5516097 0.84 PGR (0.72) PGRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4643858-A1 METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF UTERINE DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-11-05 EP claimed
WO-2024175760-A1 METHODS FOR THE TREATMENT OF ENDOMETRIOSIS Institut National de la Santé et de la Recherche Médicale (FR) 2024-08-29 WO claimed
EP-3277285-B1 ESTRIOL FOR REDUCING CORTICAL GRAY MATTER ATROPHY UNIV CALIFORNIA (US) 2024-07-17 EP claimed
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 THE SCRIPPS RESEARCH INSTITUTE 2023-11-02 US claimed
EP-3200802-B1 COMPOSITIONS AND METHODS FOR MAINTAINING COGNITIVE FUNCTION UNIV CALIFORNIA (US) 2023-07-12 EP claimed
US-20230126310-A1 COMPOSITIONS FOR CORONAVIRUS INFECTION TREATMENT AND/OR PREVENTION FRAUNHOFER GES FORSCHUNG (DE) 2023-04-27 US claimed
EP-4126234-A1 COMPOSITIONS FOR CORONAVIRUS INFECTION TREATMENT AND/OR PREVENTION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-02-08 EP claimed
US-20230000832-A1 USE OF NEUROPILIN ANTAGONISTS FOR THE TREATMENT OF ENDOMETRIOSIS ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) (FR) 2023-01-05 US claimed
EP-4065224-A1 USE OF NEUROPILIN ANTAGONISTS FOR THE TREATMENT OF ENDOMETRIOSIS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2022-10-05 EP claimed
EP-3943079-A1 THERAPEUTIC AND METHOD OF USE Predictive Therapeutics, LLC (US) 2022-01-26 EP claimed
WO-2006116498-A2 PURIFIED FORM OF TANAPROGET WYETH (US) 2006-11-02 WO claimed
US-20060009428-A1 Cyclic progestin regimens and kits WYETH (US) 2006-01-12 US claimed
EP-1531824-A4 CYCLOTHIOCARBAMATIVE DERIVATIVES AS PR MODULATORS AND USE THEREOF FOR TREATMENT OF SKIN DISORDERS WYETH CORP (US) 2005-09-21 EP claimed
EP-1515725-A4 USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS WYETH CORP (US) 2005-09-21 EP claimed
EP-1531824-A2 CYCLOTHIOCARBAMATIVE DERIVATIVES AS PR MODULATORS AND USE THEREOF FOR TREATMENT OF SKIN DISORDERS Wyeth (US) 2005-05-25 EP claimed
EP-1515725-A2 USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS Wyeth (US) 2005-03-23 EP claimed
US-20040014798-A1 Cyclothiocarbamate derivatives as progesterone receptor modulators and methods of treating skin disorders WYETH 2004-01-22 US claimed
US-20040006060-A1 Methods of treating hormone-related conditions using cyclothiocarbamate derivatives WYETH 2004-01-08 US claimed
WO-2004000801-A2 USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS WYETH (US) 2003-12-31 WO claimed
WO-2004000230-A2 CYCLOTHIOCARBAMATIVE DERIVATIVES AS PR MODULATORS AND USE THEREOF FOR TREATMENT OF SKIN DISORDERS WYETH (US) 2003-12-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006060-A1 Methods of treating hormone-related conditions using cyclothiocarbamate derivatives ESRRA, GNRHR, ESRRG PGR 46/4885NR3C1 79/4885
US-20230000832-A1 USE OF NEUROPILIN ANTAGONISTS FOR THE TREATMENT OF ENDOMETRIOSIS NRP1, PGR, TNFRSF1A PGR 2/4885NR3C1 36/4885
US-20040014798-A1 Cyclothiocarbamate derivatives as progesterone receptor modulators and methods of treating skin disorders NR5A1, MC1R, CYP17A1 PGR 7/4885NR3C1 17/4885
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 ACE2, SARS1, ACE PGR 2132/4885NR3C1 921/4885
US-20060009428-A1 Cyclic progestin regimens and kits CYP19A1, SHBG, GNRHR PGR 8/4885NR3C1 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.