SCHEMBL3880148

SCHEMBL3880148

Cc1ccc2sc(C)c(C3=C(c4nc(-c5ccccc5)sc4C)C(F)(F)C(F)(F)C3(F)F)c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARA P10276 2/20 0.38
▸ RARB P10826 2/20 0.38
▸ RARG P13631 2/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ ATP4A P20648 2/20 0.34
▸ ATP4B P51164 2/20 0.34
▸ MAPT P10636 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ GLA P06280 1/20 0.32
▸ APP P05067 2/20 0.32
▸ TP53 P04637 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ CYP1A1 P04798 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP1B1 Q16678 1/20 0.32
▸ DHODH Q02127 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3877999 0.92 RARA (0.40) RARARARBRARGAPEX1ATP4A
SCHEMBL3870541 0.92 RARA (0.38) RARARARBRARGAPEX1ATP4A
SCHEMBL3872128 0.89 RARA (0.41) RARARARBRARGAPEX1ATP4A
SCHEMBL3872932 0.86 ROCK1 (0.39) RARARARBRARGAPEX1ATP4A
SCHEMBL3870600 0.85 RARA (0.40) RARARARBRARGAPEX1ATP4A
SCHEMBL3434571 0.82 RARA (0.51) RARARARBRARGAPEX1ATP4A
SCHEMBL3879140 0.80 RARA (0.37) RARARARBRARGAPEX1ATP4A
SCHEMBL3869213 0.78 ROCK1 (0.48) RARARARBRARGAPEX1ATP4A
SCHEMBL6232786 0.78 ROCK1 (0.38) —
SCHEMBL3869530 0.77 RARA (0.40) RARARARBRARGAPEX1ATP4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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